Epitope Mapping Publications

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Research

Highly Accurate and Reproducible Diagnosis of Peanut Allergy Using Epitope Mapping

June 2020
Paul Kearney, Robert Getts, Clive Hayward, David Luta, Alex Porter, Marc Witmer, George du Toit, Gideon Lack, R. Sharon Chinthrajah, Stephen J Galli, Kari Nadeau, Galina Grishina, Mayte Suarez-Farinas, Maria Suprun, Hugh A Sampson.
medRxiv 2020.06.19.20136002; doi: https://doi.org/10.1101/2020.06.19.20136002

Novel Bead-Based Epitope Assay is a sensitive and reliable tool for profiling epitope-specific antibody repertoire in food allergy

December 2019
Maria Suprun, Robert Getts, Rohit Raghunathan, Galina Grishina, Marc Witmer, Gustavo Gimenez, Hugh A. Sampson & Mayte Suárez-Fariñas.
Scientific Reports 9, 18425 (2019).

Predicting development of sustained unresponsiveness to milk oral immunotherapy using epitope-specific antibody binding profiles.  ​​​

December 2018
Mayte Suárez-Fariñas, PhD, Maria Suprun, MPH, Helena L. Chang, MSa, Gustavo Gimenez, BS, Galina Grishina, MS, Robert Getts, PhD, Kari Nadeau, MDe, Robert A. Wood, MD, Hugh A. Sampson, MD.
Journal of Allergy and Clinical Immunology, 143 (3) , pp. 1038-1046.

A new luminex-based peptide assay to identify reactivity to baked, fermented and whole milk.

July 2018
Sackesen C, Suárez-Fariñas M, Silva R, Lin J, Schmidt S, Getts R, Gimenez G, Yilmaz EA, Cavkaytar O, Buyuktiryaki B, Soyer O, Grishina G, Sampson HA.
Allergy. 2019 Feb;74(2):327-336.

Changes in IgE and IgG4 epitope binding profiles associated with the outcome of oral immunotherapy in cow’s milk allergy.

May 2014
Savilahti EM, Kuitunen M, Valori M, Rantanen V, Bardina L, Gimenez G, Mäkelä MJ, Hautaniemi S, Savilahti E, Sampson HA.
Pediatr Allergy Immunol. 2014 May;25(3):227-35.

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay.

May 2012
Lin J, Bruni FM, Fu Z, Maloney J, Bardina L, Boner AL, Gimenez G, Sampson HA.
J Allergy Clin Immunol. 2012 May;129(5):1321-1328.e5.

Development of a novel peptide microarray for large-scale epitope mapping of food allergens.

August 2009
Lin J, Bardina L, Shreffler WG, Andreae DA, Ge Y, Wang J, Bruni FM, Fu Z, Han Y, Sampson HA.
J Allergy Clin Immunol. 2009 Aug;124(2):315-22, 322.e1-3.

Peanut epitopes for IgE and IgG4 in peanut-sensitized children in relation to severity of peanut allergy.

March 2008
Flinterman AE, Knol EF, Lencer DA, Bardina L, den Hartog Jager CF, Lin J, Pasmans SG, Bruijnzeel-Koomen CA, Sampson HA, van Hoffen E, Shreffler WG.
J Allergy Clin Immunol. 2008 Mar;121(3):737-743.e10.

Determination of epitope diversity in cow’s milk hypersensitive using microarray immunoassay.

February 2006
Wang L, Bardina L, Lencer D, Shreffler WG, Sampson HA.
Journal of Allergy and Clinical Immunology, Volume 117, Issue 2, S39.

IgE and IgG(4) epitope mapping by microarray immunoassay reveals the diversity of immune response to the peanut allergen, Ara h 2.

October 2005
Shreffler WG, Lencer DA, Bardina L, Sampson HA.
J Allergy Clin Immunol. 2005 Oct;116(4):893-9.
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