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Predicting probability of tolerating discrete amounts of peanut protein in allergic children using epitope-specific IgE antibody profiling

August 2022

Maria Suprun, Paul Kearney, Clive Hayward, Heather Butler, Robert Getts, Scott H. Sicherer, Paul J. Turner, Dianne E. Campbell, Hugh A. Sampson

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analytical validationSamantha PennAugust 31, 2022general, peanut
Prediction of cumulative tolerated dose for peanut allergic children using epitope-specific IgE antibody profiling – EAACI Poster

July 2022

Maria Suprun, Paul Kearney, Clive Hayward, Heather Butler, Robert Getts, Scott H. Sicherer, Paul Turner, Dianne E. Campbell, Hugh A. Sampson

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analytical validationSamantha PennJuly 6, 2022peanut, general
Food allergy, mechanisms, diagnosis and treatment: Innovation through a multi-targeted approach

June 2022

Sayantani B. Sindher, Andrew Long, Andrew R. Chin, Angela Hy, Vanitha Sampath, Kari C. Nadeau, R. Sharon Chinthrajah

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analytical validationSamantha PennJune 19, 2022general
Mapping Sequential IgE-Binding Epitopes on Major and Minor Egg Allergens

November 2021

Suprun M., Sicherer S.H., Wood R.A., Jones S.M., Leung D.Y.M., Burks A.W., Dunkin D., Witmer M., Grishina G., Getts R., Suárez-Fariñas M., Sampson H.A.

Int Arch Allergy Immunol 2022;183:249–261

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analytical validationSamantha PennFebruary 7, 2022egg
Accurate and reproducible diagnosis of peanut allergy using epitope mapping

June 2021

Mayte Suárez-Fariñas, Maria Suprun, Paul Kearney, Robert Getts, Galina Grishina, Clive Hayward, David Luta, Alex Porter, Marc Witmer, George du Toit, Gideon Lack, Rebecca Sharon Chinthrajah, Stephen J. Galli, Kari Nadeau, Hugh A. Sampson

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analytical validation, foundational scienceSamantha PennFebruary 6, 2022peanut, general
Ovomucoid epitope-specific repertoire of IgE, IgG4, IgG1, IgA1, and IgD antibodies in egg-allergic children

November 2020

Maria Suprun, Robert Getts, Galina Grishina, Angela Tsuang, Mayte Suárez-Fariñas, Hugh A. Sampson

Allergy. 2020;75:2633–2643.


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analytical validationSamantha PennFebruary 5, 2022general
Early epitope-specific IgE antibodies are predictive of childhood peanut allergy

August 2020

Maria Suprun MPH, Scott H. Sicherer MD, Robert A. Wood,MD, Stacie M. Jones MD, Donald Y. M. Leung MD, PhD, Alice K. Henning MS, Peter Dawson PhD, A. Wesley Burks MD, Robert Lindblad MD, Robert Getts PhD, Mayte Suarez-Fari~nas PhD, and Hugh A. Sampson MD

J Allergy Clin Immunol 2020;146:1080-8.


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analytical validationSamantha PennFebruary 5, 2022peanut
Novel Bead-Based Epitope Assay is a sensitive and reliable tool for profiling epitope-specific antibody repertoire in food allergy

December 2019

Maria Suprun, Robert Getts, Rohit Raghunathan, Galina Grishina, Marc Witmer, Gustavo Gimenez, Hugh A. Sampson & Mayte Suárez-Fariñas.

Scientific Reports 9, 18425 (2019).


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analytical validation, foundational scienceSamantha PennFebruary 3, 2022general
Predicting development of sustained unresponsiveness to milk oral immunotherapy using epitope-specific antibody binding profiles. ​​​

December 2018

Mayte Suárez-Fariñas, PhD, Maria Suprun, MPH, Helena L. Chang, MSa, Gustavo Gimenez, BS, Galina Grishina, MS, Robert Getts, PhD, Kari Nadeau, MDe, Robert A. Wood, MD, Hugh A. Sampson, MD.

Journal of Allergy and Clinical Immunology, 143 (3) , pp. 1038-1046.


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foundational scienceSamantha PennFebruary 1, 2022milk
A new luminex-based peptide assay to identify reactivity to baked, fermented and whole milk.

July 2018

Sackesen C, Suárez-Fariñas M, Silva R, Lin J, Schmidt S, Getts R, Gimenez G, Yilmaz EA, Cavkaytar O, Buyuktiryaki B, Soyer O, Grishina G, Sampson HA.

Allergy. 2019 Feb;74(2):327-336.


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analytical validation, foundational scienceSamantha PennJanuary 30, 2022peanut, milk
Changes in IgE and IgG4 epitope binding profiles associated with the outcome of oral immunotherapy in cow’s milk allergy.

May 2014

Savilahti EM, Kuitunen M, Valori M, Rantanen V, Bardina L, Gimenez G, Mäkelä MJ, Hautaniemi S, Savilahti E, Sampson HA.

Pediatr Allergy Immunol. 2014 May;25(3):227-35.


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foundational scienceSamantha PennJanuary 28, 2022peanut, general
A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay.

May 2012

Lin J, Bruni FM, Fu Z, Maloney J, Bardina L, Boner AL, Gimenez G, Sampson HA.

J Allergy Clin Immunol. 2012 May;129(5):1321-1328.e5.


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foundational scienceSamantha PennJanuary 26, 2022peanut, general
Development of a novel peptide microarray for large-scale epitope mapping of food allergens.

August 2009

Lin J, Bardina L, Shreffler WG, Andreae DA, Ge Y, Wang J, Bruni FM, Fu Z, Han Y, Sampson HA.

J Allergy Clin Immunol. 2009 Aug;124(2):315-22, 322.e1-3.


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foundational scienceSamantha PennJanuary 24, 2022peanut, general
Peanut epitopes for IgE and IgG4 in peanut-sensitized children in relation to severity of peanut allergy.

March 2008

Flinterman AE, Knol EF, Lencer DA, Bardina L, den Hartog Jager CF, Lin J, Pasmans SG, Bruijnzeel-Koomen CA, Sampson HA, van Hoffen E, Shreffler WG.

J Allergy Clin Immunol. 2008 Mar;121(3):737-743.e10.


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foundational scienceSamantha PennJanuary 22, 2022peanut, general
Determination of epitope diversity in cow’s milk hypersensitive using microarray immunoassay.

February 2006

Wang L, Bardina L, Lencer D, Shreffler WG, Sampson HA.

Journal of Allergy and Clinical Immunology, Volume 117, Issue 2, S39.


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foundational scienceSamantha PennJanuary 20, 2022peanut, milk, general
IgE and IgG(4) epitope mapping by microarray immunoassay reveals the diversity of immune response to the peanut allergen, Ara h 2.

October 2005

Shreffler WG, Lencer DA, Bardina L, Sampson HA.

J Allergy Clin Immunol. 2005 Oct;116(4):893-9.


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foundational scienceSamantha PennJanuary 18, 2022peanut, general
Measurement of peptide specific IgE as an additional tool in identifying patients with clinical reactivity to peanuts.

July 2003

Beyer K, Ellman-Grunther L, Järvinen KM, Wood RA, Hourihane J, Sampson HA.

J Allergy Clin Immunol. 2003 Jul;112(1):202-7.


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Samantha PennJanuary 16, 2022peanut, general
Role of conformational and linear epitopes in the achievement of tolerance in cow's milk allergy.

October 2001

Vila L, Beyer K, Järvinen KM, Chatchatee P, Bardina L, Sampson HA.

Clin Exp Allergy. 2001 Oct;31(10):1599-606.


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Samantha PennJanuary 14, 2022peanut, milk, general
Utility of food-specific IgE concentrations in predicting symptomatic food allergy

May 2001

Sampson, HA.

J Allergy Clin Immunol. 2001 May;107(5):891-6.

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Samantha PennJanuary 12, 2022peanut, general
 
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